Basically, Registry Healer is a tool for scanning your system's Registry for old and invalid keys. Registry Healer is particularly useful if you tend to install and uninstall a lot of programs. By putting it to work, it will help you clear out the junk that commonly fills up the Registry. Unlike similar utilities, this program doesn't simply (and dangerously) remove items from your Registry. It will attempt to correct invalid entries by finding matching folders and files that may have been moved. A separate component lets you select directories to scan. You will be able to instantly "heal" invalid entries, and safely delete some others.
Registry Healer provides a few other features for advanced users. The program provides one-click access to a registry key with the Windows RegEdit tool. Furthermore, you can highlight a reference and jump directly to the directory that it's pointing to. Finally, you can create "undo" files in the RegEdit format and full system backups. This lets you conveniently restore a Windows Registry to a previous state using native Windows? tools (even without having RegHealer installed in the system).
Registry Healer does not only delete invalid registry entries but also it searches your system for all available corrections. It can really fix the registry!
Registry Healer can also find invalid font references, obsolete Start Menu items, empty registry keys, invalid application paths, invalid registered help files and offer to correct them. So, running Registry Healer regularly will keep your registry clean and correct!

Registry Mechanic 5 - a tool for cleaning windows registry. Registry Mechanic 5 is easy in configuring and using. Registry Mechanic 5 removes programs after uninstall very good.
Download Registry Mechanic 5 here

jv16 PowerTools 2005 1.51 beta 2 - the best tool for working with registry and files. jv16 PowerTools 2005 includes tools for working with registry and files, features for tast automation and tons of configurable settings.
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Registry Trash Keys Finder - a very useful tool. Registry Trash Keys Finder finds keys in the registry, which were places by some shareware programs to perform "trial period" check. After removing those keys, most programs think they are started for the very first time. In Registry Trash Keys Finder all commands are accessible in content menu, it's possible to make the backup.
Download Registry Trash Keys Finder

CCleaner 1.18.101 - cool program for cleaning your system. CCleaner contains file cleaner (temporary files, cookies, cache, logs, removed files in the recycle bin) and registry cleaner (broken pathes, removed dlls, fonts etc). With CCleaner you can additionally set auto cleaning on computer startup, choose exact cookies to clean and directories to scan.
Download CCleaner 1.18.101

Registry Mechanic 4.0 for Windows - new version of the best tool for fixing bugs in windows registry.
Download Registry Mechanic 4.0 for Windows

Registry Defragmentation v6.6 - a pretty useful utility for cleaning, defragmenting and restoring the registry. Registry Defragmentation v6.6 is pretty light (1,3Mb) and very fast.
Download Registry Defragmentation v6.6 here

jv16 PowerTools 2005 1.50.271 - final version has been released. jv16 PowerTools 2005 is the program for working with registry and files for cleaning the system. jv16 PowerTools 2005 includes task automation services, a lot of changeable parameters etc.
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CCleaner 1.17.090 - crap cleaner. CCleaner removes remporary files, cleans history, cookies etc. CCleaner searches not only for standard garbage (gid, tmp, bak) files, but also removes program specific things like Adobe Acrobat, eMule, Google Toolbar, Kazaa, Microsoft Office, Nero Burning ROM, Opera and WinRAR.
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CCleaner 1.17.90 - a good freeware tool for system cleaning. CCleaner includes file cleaner (tempopary files, cache, logs, cookies, logs, files in recycle bin) and registry cleaner (broken pathes, removed dlls, fonts, etc). CCleaner can additionaly set auto-cleaning on the system start-up, choose specified cookies and folders for scanning.
Download CCleaner 1.17.90 here